MABF233

Anti-HLA-C Antibody, clone DT9

clone DT9, from mouse

• Synonym(e): HLA class I histocompatibility antigen,Cw-1 alpha chain, MHC class I antigen Cw*1
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: DT9, monoclonal
• Application: FACS, IP
• Citations: 7

Eigenschaften

• biological source: mouse
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: DT9, monoclonal
• species reactivity: human
• technique(s): flow cytometry: suitable, immunoprecipitation (IP): suitable
• isotype: IgG2bκ
• UniProt accession no.: P10321
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... HLA-C(3107)

Beschreibung

General description

41 kDa calculated

HLA-C, also known as HLA class I histocompatibility antigen, Cw-1 alpha chain, also known as MHC class I antigen Cw*1, and encoded by the gene HLA-C/HLAC. It contains an alpha and beta (beta-2-microglobulin) chain and interacts with the human herpesvirus 8 MIR1 protein.

The previously assigned protein identifier P30499 has been merged into P10321. Full details can be found on the UniProt database.

Immunogen

Purified tamarin MHC class I molecules corresponding to human HLA-C.

Application

Anti-HLA-C Antibody, clone DT9 is an antibody against HLA-C for use in flow cytometry & IP.

Flow Cytometry Analysis: A representative lot from an independent laboratory detected HLA-C in peripheral blood CD3+ cells from 200 healthy human donors (Apps, R., et al. (2013). Science. 340(6128):84-91.).

Flow Cytometry Analysis: A representative lot from an independent laboratory detected HLA-C in human PBMCs (Corrah, T. W., et al. (2011). J Virol. 85(7):3367-3374.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated HLA-C from various human cell lines (Braud, V. M., et al. (1998). Curr Biol. 8(1):1-10.).

Research Category
Inflammation & Immunology

Research Sub Category
Inflammation & Autoimmune Mechanisms

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Flow Cytometry in human PBMCs.

Flow Cytometry Analysis: 1 µg of this antibody detected HLA-C in 1X10E6 human PBMCs.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable