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MAB5596

Anti-HCN2 Antibody

culture supernatant, Chemicon®

Synonym(e):

Hyperpolarization-activated and cyclic nucleotide-gated channel 2

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PackungsgrößeSKUVerfügbarkeitPreis
100 μL
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€ 361,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
monoclonal
Application:
IHC, WB
Citations:
3

€ 361,00


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biological source

rat

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

monoclonal

species reactivity

mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

mouse ... Hcn2(15166)
rat ... Hcn2(114244)

Immunogen

Synthetic peptide from rat HCN2.

Application

Anti-HCN2 Antibody is an antibody against HCN2 for use in IH & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot on rat and mouse retina. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.

Immunohistochemistry on rat and mouse retina.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

HCN2 (Hyperpolarization-activated and cyclic nucleotide-gated channel 2). The antibody recognizes both the glycosyated and deglycosylated form of HCN2. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.

Physical form

Cultured supernatant containing 0.05% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
AB5884MAB5598SAB5200024
biological source

rat

biological source

rabbit

biological source

rat

biological source

mouse

Gene Information

mouse ... Hcn2(15166)
rat ... Hcn2(114244)

Gene Information

human ... HCN1(348980)

Gene Information

mouse ... Hcn3(15168)

Gene Information

rat ... HCN1(84390)

antibody form

culture supernatant

antibody form

affinity purified immunoglobulin

antibody form

culture supernatant

antibody form

purified immunoglobulin

species reactivity

mouse, rat

species reactivity

rat

species reactivity

mouse, rat

species reactivity

mouse, rat, human

clone

monoclonal

clone

polyclonal

clone

TLL 6C5, monoclonal

clone

S70-28, monoclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated


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Lagerklasse

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Joon Ha Park et al.
International journal of molecular medicine, 44(5), 1801-1810 (2019-10-02)
Hyperpolarization‑activated cyclic nucleotide‑gated (HCN) channels have been known to participate in the regulation of neuronal excitability, synaptic transmission and long‑term potentiation in the hippocampus. The present study investigated transient ischemia‑induced changes of HCN1 and HCN2 expressions in the Cornu Ammonis
Stuart M Cain et al.
Pflugers Archiv : European journal of physiology, 467(6), 1367-1382 (2014-06-24)
Burst-firing in distinct subsets of thalamic relay (TR) neurons is thought to be a key requirement for the propagation of absence seizures. However, in the well-regarded Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model as yet there has been no



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