MAB5320

Anti-α-Synuclein (SNCA) Antibody

CHEMICON^®, mouse monoclonal, 7B12.2

• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Clone: 7B12.2, monoclonal
• Species reactivity: human
• Application: IHC, WB
• Citations: 20

Eigenschaften

• Produktname: Anti-Synuclein α Antibody, clone 7B12.2, culture supernatant, clone 7B12.2, Chemicon^®
• biological source: mouse
• Quality Segment: 100
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: 7B12.2, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable, western blot: suitable
• isotype: IgG
• NCBI accession no.: NM_000345.2, NM_007308.1
• UniProt accession no.: P37840
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... SNCA(6622)

Beschreibung

General description

15-18 kDa

Immunogen

Recombinant human alpha synuclein.

Application

Anti-Synuclein Antibody, α, clone 7B12.2 detects level of Synuclein & has been published & validated for use in IH & WB.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Western blotting on recombinant alpha synuclein: 1:2,000-1:4,000.

Lane 1: Recombinant human alpha synuclein

Lane 2: Recombinant human beta synuclein

Lane 3: Recombinant human gamma synuclein

Immunohistochemistry (frozen sections): 1:250-1:500

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with alpha Synuclein. By Western blot the antibody shows no reactivity with beta or gamma synuclein. This antibody was shown to stain Lewy bodies in frozen section of human brain with Parkinson′s disease and glial inclusions in frozen section of human brain with Multiple System Atrophy.

Physical form

UnPurified tissue culture supernatant from a perfusion system, filtered through a 0.2μ micron membrane prior to vialing. Product contains 20%FBS and Ciprofloxacin at final concentration of 10μg/mL.

Unpurified

Preparation Note

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Brain tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: 04-1053

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable