MAB394
Anti-Dopamine β Hydroxylase-SAP Antibody, clone 4F10.2
clone 4F10.2, Chemicon®, from mouse
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 25 μg | Warenkorb auf Verfügbarkeit prüfen | € 179,00 | |
| 250 μg | Warenkorb auf Verfügbarkeit prüfen | € 4.850,00 |
Über diesen Artikel
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
saporin
Clone:
4F10.2, monoclonal
Application:
immunolesioning
Citations:
8
Technischer Dienst
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Unterstützung erhaltenbiological source
mouse
Quality Level
conjugate
saporin
antibody product type
primary antibodies
clone
4F10.2, monoclonal
species reactivity
rat
packaging
antibody small pack of 25 μg
manufacturer/tradename
Chemicon®
technique(s)
immunolesioning: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
rat ... Dbh(25699)
Application
Anti-Dopamine β Hydroxylase-SAP Antibody, clone 4F10.2 detects level of Dopamine β Hydroxylase & has been published & validated for use in 0.
Biochem/physiol Actions
Dopamine b-HydroxylaseDBH is a single gene product that exists as a cytosolic enzyme, as a membrane protein and is secreted into the circulation (Lewis & Asnani, 1992). Because of its residence time as a plasma membrane-bound protein, it is able to be used as a targeting agent for neurons. The target neurons include postganglionic sympathetic neurons and all noradrenergic and adrenergic neurons of the central nervous system. As such anti-DBH-SAP can be used for the production of acute peripheral autonomic failure in a model for the human disease. It can also be used for the analysis of the behavioral effects of noradrenergic or adrenergic ablation. When injected intraventricularly, noradrenergic neurons of the locus coeruleus are eliminated (Wiley & Lappi, 1994). The antibody and immunotoxin undergo retrograde transport.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Dieser Artikel | |||
|---|---|---|---|
| biological source mouse | biological source rabbit | biological source sheep | biological source rabbit |
| Gene Information rat ... Dbh(25699) | Gene Information human ... DBH(1621) | Gene Information human ... DBH(1621) | Gene Information human ... DBH(1621) |
| clone 4F10.2, monoclonal | clone polyclonal | clone polyclonal | clone polyclonal |
| species reactivity rat | species reactivity bovine, guinea pig, rat, human, feline, rabbit | species reactivity monkey, human | species reactivity rat, human, bovine, sheep |
| conjugate saporin | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
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Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Yuefeng Lu et al.
Anatomical record (Hoboken, N.J. : 2007), 295(7), 1192-1201 (2012-06-08)
Locus coeruleus (LC) consists of a densely packed nuclear core and a surrounding plexus of dendritic zone, which is further divided into several subregions. Whereas many limbic-related structures topographically target specific subregions of the LC, the precise projections from two
Jonathan N Flak et al.
The European journal of neuroscience, 39(11), 1903-1911 (2014-04-29)
Chronic variable stress (CVS) exposure modifies the paraventricular nucleus of the hypothalamus (PVN) in a manner consistent with enhanced central drive of the hypothalamo-pituitary-adrenocortical (HPA) axis. As previous reports suggest that post-stress enhancement of norepinephrine (NE) action contributes to chronic
Carlos Blanco-Centurion et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(51), 14041-14048 (2007-12-21)
The hypocretin (HCRT) neurons are located only in the perifornical area of the lateral hypothalamus and heavily innervate the cholinergic neurons in the basal forebrain (BF), histamine neurons in the tuberomammillary nucleus (TMN), and the noradrenergic locus ceruleus (LC) neurons
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB394-25UG | 04053252501647 |
| MAB394-250UG | 04053252724565 |