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MAB1999

Anti-Integrin αVβ1 Antibody

CHEMICON®, mouse monoclonal, HA5

Synonym(e):

VLA-5

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PackungsgrößeSKUVerfügbarkeitPreis
100 μg
Warenkorb auf Verfügbarkeit prüfen
€ 401,00

Über diesen Artikel

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
HA5, monoclonal
Species reactivity:
pig, human
Application:
FACS, IP
Citations:
44

€ 401,00


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Produktname

Anti-Integrin α5β1 Antibody, clone HA5, clone HA5, Chemicon®, from mouse

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

HA5, monoclonal

species reactivity

pig, human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunoprecipitation (IP): suitable

isotype

IgG2bκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGA5(3678)

Application

Anti-Integrin α5β1 Antibody, clone HA5 detects level of Integrin α5β1 & has been published & validated for use in FC & IP.
Immunoprecipitation of VLA-5 integrins from lysate of 10E6 cell equivalent requires 2 μg of MAB1999.

Flow cytometry: 10 μg/mL

Does not detect VLA-5 by Western blot.

MAB1999 does not affect VLA-5 mediated cell adhesion to fibronectin.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with the fibronectin receptor VLA-5 (alpha-5beta-1) integrin complex.

Physical form

Format: Purified
Purified immunoglobulin from Protein A chromatography. Liquid in 0.02 M PB pH 7.6, 0.25 M NaCl, 0.1% sodium azide.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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MAB2575MAB1956ZMAB1998Z
Gene Information

human ... ITGA5(3678)

Gene Information

human ... ITGA5(3678)

Gene Information

human ... ITGA5(3678)

Gene Information

human ... ITGA2(3673)

clone

HA5, monoclonal

clone

BMC5, monoclonal

clone

P1D6, monoclonal

clone

BHA2.1, monoclonal

antibody form

purified immunoglobulin

antibody form

ascites fluid

antibody form

purified antibody

antibody form

purified immunoglobulin

biological source

mouse

biological source

rat

biological source

mouse

biological source

mouse

species reactivity

pig, human

species reactivity

mouse

species reactivity

human

species reactivity

human, pig

technique(s)

flow cytometry: suitable, immunoprecipitation (IP): suitable

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable

technique(s)

immunohistochemistry: suitable

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Lagerklasse

12 - Non Combustible Liquids



Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Yuya Sato et al.
The Journal of biological chemistry, 284(18), 11873-11881 (2009-03-12)
Recently we reported that N-glycans on the beta-propeller domain of the integrin alpha5 subunit (S-3,4,5) are essential for alpha5beta1 heterodimerization, expression, and cell adhesion. Herein to further investigate which N-glycosylation site is the most important for the biological function and
Qinglei Hang et al.
The Journal of biological chemistry, 290(49), 29345-29360 (2015-10-21)
Integrin α5β1-mediated cell adhesion regulates a multitude of cellular responses, including cell proliferation, survival, and cross-talk between different cellular signaling pathways. Integrin α5β1 is known to convey permissive signals enabling anchorage-dependent receptor tyrosine kinase signaling. However, the effects of integrin
Ingrid Burvenich et al.
Molecular cancer therapeutics, 7(12), 3771-3779 (2008-12-17)
This study identifies and characterizes the antigen recognized by monoclonal antibody (mAb) 14C5. We compared the expression of antigen 14C5 with the expression of eight integrin subunits (alpha1, alpha2, alpha3, alphav, beta1, beta2, beta3, and beta4) and three integrin heterodimers



Global Trade Item Number

SKUGTIN
MAB199904053252315848

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