AB9870

Anti-STIM1 Antibody

Chemicon^®, from rabbit

• Synonym(e): Stromal interaction molecule 1
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 9

Eigenschaften

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human, mouse
• manufacturer/tradename: Chemicon^®
• technique(s): western blot: suitable
• UniProt accession no.: Q13586
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... CAV1(857), NUP98(4928), ORAI1(84876)

Beschreibung

General description

80 kDa

TRP (transient receptor potential)-related ion channels (TRPCs) have been postulated as candidates for forming both receptor-operated (ROCE) and capacitative Ca2+ entry channels across the plasma membrane. ER transmembrane protein STIM1 senses the depletion of Ca2+ from ER stores. Orai proteins, interacting with TRPCs, act as regulatory subunits that confers STIM1-mediated store depletion sensitivity to these channels and regulate Ca2+ influx through the plasma membrane.

Immunogen

Synthetic Linear Peptide

Application

Anti-STIM1 Antibody is an antibody against STIM1 for use in WB.

Optimal working dilutions must be determined by the end user.

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

Biochem/physiol Actions

Catalogue No. AB9870 recognizes the C-Terminus of STIM1.

Physical form

Format: Purified

Protein A purified

Purified in PBS with 0.05% NaN3

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Analysis Note

Control
Jurkat lysate.

Routinely evaluated in western blotting using Jurkat lysate.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable