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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 100 μL | Warenkorb auf Verfügbarkeit prüfen | € 529,00 |
Über diesen Artikel
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
rat ... Grin2B(24410)
Immunogen
Application
Neuroscience
Neurotransmitters & Receptors
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Physical form
Preparation Note
Legal Information
Disclaimer
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| antibody form affinity purified immunoglobulin | antibody form affinity isolated antibody | antibody form affinity purified immunoglobulin | antibody form affinity isolated antibody |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| biological source rabbit | biological source rabbit | biological source mouse | biological source rabbit |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in wet ice |
| Gene Information rat ... Grin2B(24410) | Gene Information human ... GRIN1(2902) | Gene Information human ... GRIN1(2902) | Gene Information rat ... Grin2b(24410) |
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Lagerklasse
10 - Combustible liquids
wgk
WGK 2
Analysenzertifikate (COA)
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Verwandter Inhalt
Glutamate is an excitatory neurotransmitter found in the synaptic vesicles of glutamatergic synapses. The post-synaptic neurons in these synapses contain ionotropic and metabotropic glutamate receptors. Glutamate binds to AMPA (α-amino-3-hydroxy-5- methylisoxazole-4-propionic acid) subtype glutamate receptors, leading to sodium influx into the post-synaptic cell and resulting in neuronal excitability and synaptic transmission. The NMDA (N-methyl-d-aspartate) subtype glutamate receptors, on the other hand, regulate synaptic plasticity, and can influence learning and memory. The metabotropic g-protein coupled mGluRs modulate downstream calcium signaling pathways and indirectly influence the synapse’s excitability. The synaptic architecture includes intracellular scaffolding proteins (PSD-95, GRIP), intercellular cell adhesion molecules (NCAMs, N-Cadherins), and a variety of signaling proteins (CaMKII/PKA, PP1/PP2B). Processes critical for synaptic transmission and plasticity are influenced by these molecules and their interactions. When the function of these molecules is disrupted, it leads to synaptic dysfunction and degeneration, and can contribute to dementia as seen in Alzheimer’s disease.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB5403 | 04053252331237 |



