AB3530P
Anti-Epithelial Sodium Channel-α Antibody
Chemicon®, from rabbit
Synonym(e):
ENaC-alpha
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
affinity purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Aufgereinigt durch
affinity chromatography
Speziesreaktivität
rat
Hersteller/Markenname
Chemicon®
Methode(n)
western blot: suitable
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... SCNN1A(6337)
Spezifität
Recognizes rat Epithelial Sodium Channel alpha (ENaC alpha). The immunogen shows no significant sequence homology with other ENaC subunits.
Immunogen
A 20 amino acid peptide sequence near the N-terminus of rat ENaC alpha (Linguela et al. 1993; Canessa et al.
1993; Snyder et al. 1994; Waldmann et al. 1995; Kreutz et al. 1997; Voilley et al.
1994; McDonald et al. 1994; Ludwig et al. 1998; Garty & Palmer 1997).
1993; Snyder et al. 1994; Waldmann et al. 1995; Kreutz et al. 1997; Voilley et al.
1994; McDonald et al. 1994; Ludwig et al. 1998; Garty & Palmer 1997).
Anwendung
Research Category
Neurowissenschaft
Neurowissenschaft
Research Sub Category
Ionenkanäle & -transporter
Neuroinflammation & Schmerz
Ionenkanäle & -transporter
Neuroinflammation & Schmerz
Anti-Epithelial Sodium Channel-α Antibody is an antibody against Epithelial Sodium Channel-α for use in WB.
Western blot: 1-10 μg/mL using ECL and rat brain membrane preparations, see membrane preparation protocol under Technical Support\General Technical Info\General Methods at www.chemicon.com.
83-90kDa band is expected.
Optimal working dilutions must be determined by the end user.
83-90kDa band is expected.
Optimal working dilutions must be determined by the end user.
Zielbeschreibung
83-90kDa
Physikalische Form
ImmunoAffinity Purified
Affinity Purified immunoglobulin. Liquid in phosphate buffered saline, pH 7.4, containing 0.1% BSA and 0.1% sodium azide.
Lagerung und Haltbarkeit
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hinweis zur Analyse
Control
Epithelial structures
Epithelial structures
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Gaizun Hu et al.
American journal of hypertension, 36(9), 509-516 (2023-05-12)
Our previous studies showed that renal medullary sphingosine-1-phosphate receptor 1 (S1PR1) mediated sodium excretion, high salt intake increased S1PR1 level, deoxycorticosterone acetate (DOCA) blocked high salt-induced S1PR1 in the renal medulla, and that conditional knockout of S1PR1 in the collecting
Estrogen increases ENaC activity via PKC? signaling in renal cortical collecting duct cells.
Yusef, YR; Thomas, W; Harvey, BJ
Physiological Reports null
L R E Pedersen et al.
Acta physiologica (Oxford, England), 206(2), 142-149 (2012-06-12)
We wished to determine the effect of continuous β-receptor stimulation on alveolar fluid clearance and to elucidate the mechanisms behind this effect. Alveolar fluid clearance was measured in anaesthetized rats pretreated for 72 h with the β-agonist isoproterenol (200 μg kg(-1) h(-1) sc)
Noriatsu Shigemura et al.
Nutrients, 11(9) (2019-09-25)
The systemic renin-angiotensin system (RAS) is an important regulator of body fluid and sodium homeostasis. Angiotensin II (AngII) is a key active product of the RAS. We previously revealed that circulating AngII suppresses amiloride-sensitive salt taste responses and enhances the
Eman Y Gohar et al.
Journal of the American Heart Association, 11(5), e020450-e020450 (2022-02-23)
Background Premenopausal women are less likely to develop hypertension and salt-related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined. Here, we determined whether female rats have a
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