AB3232

Anti-Low Density Lipoprotein Antibody, HOCL oxidized

serum, Chemicon^®

• Synonym(e): LDL
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: serum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Speziesreaktivität: human
• Hersteller/Markenname: Chemicon^®
• Methode(n): ELISA: suitable; immunohistochemistry: suitable
• Versandbedingung: dry ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... LDLR(3949)

Beschreibung

Spezifität

Reacts strongly and very specifically with HOCL-LDL. By time resolved fluorescence there was no detectable cross reactivity to unmodified LDL has been observed. However weak cross reactivity with MDA-LDL (20%), HNE-LDL (5%) and minimally modified LDL (5%) was observed. By Western blot no detectable cross reactivity to unmodified LDL was observed. Weak cross reactivity (<10%) was detected with MDA-LDL, HNE-LDL and 24 hour Cu2+ oxidized LDL. By ELISA the antibody bound to early and late stages of HOCL-LDL but only weakly (<5%) to several other modifications including MDA-LDL, Cu2-ox-LDL, MDA-HSA and native LDL.

Immunogen

Epitope: HOCL oxidized

Hypochlorite-modified LDL.

Anwendung

Research Category
Stoffwechsel

Research Sub Category
Lipidstoffwechsel & Gewichtsregulierung

Immunohistochemistry: 1:50-1:400

ELISA: 1:400-1:4,000

Optimal working dilutions must be determined by the end user.

This Anti-Low Density Lipoprotein Antibody, HOCL oxidized is validated for use in ELISA, IH for the detection of Low Density Lipoprotein.

Physikalische Form

Rabbit serum.

Lagerung und Haltbarkeit

Maintain lyophilized material at -20°C for up to 6 months After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable