605160

Thrombin, Plasminogen-Free, Bovine

• Synonym(e): Thrombin, Plasminogen-Free, Bovine
• CAS-Nummer: 9002-04-4
• UNSPSC-Code: 12352204
• NACRES: NA.25

Eigenschaften

• Form: lyophilized
• Qualitätsniveau: 100
• Spezifische Aktivität: ≥1000 NIH units/mg protein
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated
• Löslichkeit: water: 1 mg/mL
• Fremdaktivität: Plasminogen, none detected (by rocket IEP)
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Native, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin. Note: 1 KU = 1000 units.

Native, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin. Serine protease formed in the plasma during the coagulation process by activation of prothrombin by a complex of Factor Xa, Factor Va, phospholipid, and Ca²⁺. Thrombin cleaves Arg-Gly bonds in specific sequences only. The best characterized activity of thrombin is the conversion of fibrinogen to fibrin in the clotting process. Inhibited by AEBSF (Cat. No. 101500) Antithrombin (Cat. No. 169756), PMSF (Cat. No. 52332), and TLCK (Cat. No. 616382). Note: 1 KU = 1000 units.

Warnhinweis

Toxicity: Harmful (C)

Einheitendefinition

One unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.

Physikalische Form

Lyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.

Rekonstituierung

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.

Hinweis zur Analyse

Complete activation from homogeneous bovine prothrombin by SDS-PAGE

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H315,H319,H334,H335
• P-Sätze: P261 - P264 - P271 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable