524742

Phosphodiesterase 3A, Active, Human, Recombinant, S. frugiperda

• Synonym(e): cAMP-specific phosphodiesterase 3A, PDE3A
• NACRES: NA.54
• UNSPSC Code: 12352203
• Specific activity: ≥0.5 U/μL
• Recombinant: expressed in insect cells (S. frugiperda)

Eigenschaften

• recombinant: expressed in insect cells (S. frugiperda)
• Quality Segment: 100
• form: liquid
• specific activity: ≥0.5 U/μL
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Beschreibung

General description

Full-length, recombinant, human phosphodiesterdase 3A (PDE3A) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE3A is expressed primarily in cardiac and vascular myocytes and platelets. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.

Physical form

In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.

Preparation Note

Following reconstitution, aliquot and freeze (-70°C).

Other Notes

One unit is defined as the amount of enzyme that is required to convert 1 pmol cAMP to AMP per min at pH 7.5, 30°C.

Shakur, Y., et al. 2000. J. Biol. Chem.275, 38749.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• signalword: Danger
• hcodes: EUH430
• pcodes: P201 - P202 - P273 - P391 - P405 - P501
• Hazard Classifications: ED ENV 1