5.08314

KN-92

InSolution, ≥95%, 5 mM in DMSO, Useful as a negative control for KN-93

• Synonym(e): InSolution KN-92, 2-(N-(4-Methoxybenzenesulfonyl))amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, Phosphate, ( E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide, Phosphate, 2-(N-(4-Methoxybenzenesulfonyl))amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, Phosphate, (E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide, Phosphate
• Empirische Formel (Hill-System): C₂₄H₂₅ClN₂O₃S · xH₃PO₄
• CAS-Nummer: 1135280-28-2
• Molekulargewicht: 456.98
• MDL number: MFCD24369012
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: liquid
• Quality level: 100
• Storage condition: OK to freeze, avoid repeated freeze/thaw cycles, desiccated (hygroscopic), protect from light

Eigenschaften

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, avoid repeated freeze/thaw cycles, desiccated (hygroscopic), protect from light
• storage temp.: −70°C
• SMILES string: [P](=O)(O)(O)O.[S](=O)(=O)(Nc2c(cccc2)CN(C\C=C\c3ccc(cc3)Cl)C)c1ccc(cc1)OC
• InChI: 1S/C24H25ClN2O3S.H3O4P/c1-27(17-5-6-19-9-11-21(25)12-10-19)18-20-7-3-4-8-24(20)26-31(28,29)23-15-13-22(30-2)14-16-23;1-5(2,3)4/h3-16,26H,17-18H2,1-2H3;(H3,1,2,3,4)/b6-5+;
• InChI key: XRQHWVVDNMJDEQ-IPZCTEOASA-N

Beschreibung

General description

Useful as a negative control for KN-93 (Cat. No. 422708), a Ca²⁺/CaM kinase II inhibitor.

Biochem/physiol Actions

Reversible: yes

Cell permeable: yes

Packaging

Packaged under inert gas

Physical form

A 5 mM (500 µg/180 µL) sterile-filtered solution of KN-92 (Cat. No. 422709) in DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 3 months at -20°C.

Other Notes

Fan, G.H., et al. 1999. Mol. Pharmacol.56, 39.
Fan, G.H., et al. 1997. Neuropharmacology36, 1763.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 2
• flash_point_f: 188.6 °F - (refers to pure substance)
• flash_point_c: 87 °C - (refers to pure substance)