48-612MAG

MILLIPLEX^® Total Akt/mTOR Magnetic Bead 11-Plex Kit – Multiplex-Zellsignalisierungsassay

Premixed Akt/mTOR Total 11-Plex Cell Signaling Panel

• Synonym(e): Magnetperlen-Assay
• NACRES: NA.47
• UNSPSC Code: 12161503

Eigenschaften

• Produktname: MILLIPLEX^® Total Akt/mTOR Magnetic Bead 11-Plex Kit – Multiplex-Zellsignalisierungsassay,
• Quality Segment: 200
• description: Premixed Akt/mTOR Total 11-Plex Cell Signaling Panel
• species reactivity: human
• packaging: pkg of 1 ea
• manufacturer/tradename: Milliplex^®
• technique(s): multiplexing: suitable
• input: cell lysate
• detection method: fluorometric (Luminex^® xMAP^® technology)
• shipped in: wet ice
• storage temp.: 2-8°C

Beschreibung

General description

This panel targets total expression of key proteins in the PI3K/Akt/mTOR signaling pathway, which regulates cell growth, metabolism, and survival. It includes total levels of Akt isoforms, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6. These proteins are frequently altered in cancer, diabetes, and neurodegenerative diseases.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 11 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: Akt (Total), GSK3α (Total), GSK3β (Total), IGF-1R (Total), IR (total), IRS1 (Total), mTOR (Total), p70S6K (Total), PTEN (Total), RPS6 (Total), TSC2 (Total)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate^™Control Assays).

Features and Benefits

• Simultaneously detect total expression of 11 proteins in the PI3K/Akt/mTOR signaling pathway
• Includes Akt1, Akt2, Akt3, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6
• Magnetic bead-based format ensures reproducibility and efficient processing
• Compatible with cell lysates from cancer, metabolic, and signaling studies
• Ideal for oncology, metabolism, and cell biology research
• Fast, convenient alternative to Western Blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corporation

MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Sicherheitshinweise

• pictograms: GHS07
• Lagerklasse: 10-13 - German Storage Class 10 to 13
• signalword: Danger
• hcodes: H319,H412,EUH430
• pcodes: P201 - P202 - P273 - P391 - P405 - P501
• Hazard Classifications: Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2
• wgk: WGK 2