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07-1815

Anti-FIP200 Antibody

serum, from rabbit

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Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
1


biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse

technique(s)

western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

rat ... Stx8(59074)

General description

200 kDa
Focal adhesion kinase family interacting protein of 200 kDa (FIP200) is a novel protein inhibitor for focal adhesion kinase (FAK). FIP200 inhibits kinase activity and associated cellular functions, such as cell adhesion, spreading, and motility in fibroblasts by binding directly to FAK.

Immunogen

Epitope: C-terminus
The immunogen was a synthetic peptide corresponding to the C-terminal region of FIP200.

Application

Detect FIP200 using this Anti-FIP200 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

Biochem/physiol Actions

This antibody recognizes the C-terminal region of FIP200.

Physical form

Unpurified rabbit serum in buffer containing 0.05% sodium azide.

Preparation Note

Stable for 2 years at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

Analysis Note

Evaluated by western blot on HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect FIP200 in HEK293 cell lysate.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
MABC128MABC114506-255-I
clone

polyclonal

clone

14E11.2, monoclonal

clone

73.3, monoclonal

clone

polyclonal

antibody form

serum

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified antibody

species reactivity

human, rat, mouse

species reactivity

human, mouse

species reactivity

mouse

species reactivity

human, rat, mouse

biological source

rabbit

biological source

mouse

biological source

mouse

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

UniProt accession no.

Q86YR4

UniProt accession no.

Q8TDY2

UniProt accession no.

P97321

UniProt accession no.

Q62120


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Lagerklasse

10 - Combustible liquids

wgk

WGK 1



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Zhengwei Ma et al.
The Journal of clinical investigation, 130(9), 5011-5026 (2020-08-18)
Dysregulation of autophagy in diabetic kidney disease (DKD) has been reported, but the underlying mechanism and its pathogenic role remain elusive. We show that autophagy was inhibited in DKD models and in human diabetic kidneys. Ablation of autophagy-related gene 7



Global Trade Item Number

SKUGTIN
07-181504053252470899

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