05-233
Anti-Nitrotyrosin-Antikörper, Klon 1A6
clone 1A6, Upstate®, from mouse
Synonym(e):
Anti-Nitrotyrosin-Antikörper
Größe auswählen
| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 100 μg | Warenkorb auf Verfügbarkeit prüfen | € 545,00 |
Über diesen Artikel
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1A6, monoclonal
species reactivity
vertebrates
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG2bκ
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... NOS1(4842)
General description
Application
Physical form
Analysis Note
Immunhistochemie: Hirnschnitte von Menschen mit Alzheimer-Krankheit (in Methacarn fixiert), Leber der Maus
Immunblot: Nitriertes BSA
indirekter ELISA: nitriertes BSA
Indirekte Immunfluoreszenz: A549-Zellen, die metabolisch mit 3-Nitrotyrosin markiert sind
Legal Information
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| species reactivity vertebrates | species reactivity - | species reactivity - | species reactivity human |
| clone 1A6, monoclonal | clone polyclonal | clone polyclonal | clone polyclonal |
| biological source mouse | biological source rabbit | biological source rabbit | biological source rabbit |
| antibody form purified immunoglobulin | antibody form affinity purified immunoglobulin | antibody form affinity isolated antibody | antibody form affinity isolated antibody |
| technique(s) immunocytochemistry: suitable, immunoprecipitation (IP): suitable, immunohistochemistry: suitable, western blot: suitable | technique(s) immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable | technique(s) immunoprecipitation (IP): suitable | technique(s) immunocytochemistry: suitable |
| Gene Information human ... NOS1(4842) | Gene Information human ... NOS1(4842) | Gene Information human ... NOS1(4842) | Gene Information human ... NOS1(4842) |
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Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysenzertifikate (COA)
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Verwandter Inhalt
"Redox reactions are powerful chemical processes that involve the reduction and oxidation of proteins and metabolites found in living things. The mechanisms that regulate them are key to maintaining homeostasis and the balance between good health and disease pathology. Oxidative stress is the state where the delicate balance of redox biology is upset, and the pathology of oxidative stress are the cellular consequences to such an imbalance."
"Aging: getting older, exhibiting the signs of age, the decline in the physical (and mental) well-being over time, leading to death. Since the beginning of time, man has been obsessed with trying to slow down, stop, or even reverse the signs of aging. Many have gone as far as experimenting with nutritional regimens, eccentric exercises, fantastic rituals, and naturally occurring or synthetic wonder-elements to evade the signs of normal aging. Biologically speaking, what is aging? And what does the latest research tell us about the possibility of discovering the elusive “fountain of youth”? Many advances in our understanding of aging have come from systematic scientific research, and perhaps it holds the key to immortality. Scientifically, aging can be defined as a systems-wide decline in organismal function that occurs over time. This decline occurs as a result of numerous events in the organism, and these events can be classified into nine “hallmarks” of aging, as proposed by López-Otin et al. (2013). Several of the pathologies associated with aging are a direct result of these events going to extremes and may also involve aberrant activation of proliferation signals or hyperactivity. The hallmarks of aging have been defined based on their fulfillment of specific aging related criteria, such as manifestation during normal aging, acceleration of aging if experimentally induced or aggravated, and retardation of aging if prevented or blocked, resulting in increased lifespan. The nine hallmarks of aging are genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. The biological processes underlying aging are complex. By understanding the hallmarks in greater detail, we can get closer to developing intervention strategies that can make the aging process less of a decline, and more of a recline."