Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others.
Immunogen
Nitrated KLH
Anwendung
Research Category Zelluläre Signaltransduktion
Research Sub Category Allgemeine Posttranslationsmodifikation
Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody is an antibody against Nitrotyrosine for use in IP.
Qualität
Evaluated by immunoprecipitation on A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).
Stable for 1 year at 2-8°C from date of shipment. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Hinweis zur Analyse
Control A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 2
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Clinical cancer research : an official journal of the American Association for Cancer Research, 24(8), 1891-1904 (2018-01-25)
Purpose: mAbs are used to treat solid and hematologic malignancies and work in part through Fc receptors (FcRs) on natural killer cells (NK). However, FcR-mediated functions of NK cells from patients with cancer are significantly impaired. Identifying the mechanisms of
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