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Merck

04-294

Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5

clone 19G5, Upstate®, from mouse

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100 μG

€ 372,00

€ 372,00


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Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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Produktname

Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5, clone 19G5, Upstate®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

19G5, monoclonal

species reactivity

canine, rat, mouse, human

manufacturer/tradename

Upstate®

technique(s)

ELISA: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

phosphorylation (pTyr1112)

Quality Level

Gene Information

human ... ERBB2(2064)
mouse ... Erbb2(13866)

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Dieser Artikel
05-48404-29307-841
biological source

mouse

biological source

mouse

biological source

mouse

biological source

rabbit

antibody form

purified immunoglobulin

antibody form

purified antibody

antibody form

purified antibody

antibody form

affinity isolated antibody

clone

19G5, monoclonal

clone

20G3, monoclonal

clone

7F8, monoclonal

clone

polyclonal

species reactivity

canine, rat, mouse, human

species reactivity

human, mouse

species reactivity

mouse, human, canine

species reactivity

mouse, human

UniProt accession no.

P04626

UniProt accession no.

P00533

UniProt accession no.

P04626

UniProt accession no.

P06213

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

Analysis Note

Control
Includes EGF treated SKOV-3 lysate as a positive control
Routinely evaluated by immunoblot.

Application

Detect phosho-erbB2/Her2 (Tyr1112) using this Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5 validated for use in ELISA & WB.

Biochem/physiol Actions

Recognizes phosphorylated domain of erbB2/Her2 on Tyrosine 1112

General description

185 kDa

Immunogen

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Tyr1112 in human erbB2/Her2

Physical form

Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklasse

10 - Combustible liquids


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L N Klapper et al.
Cancer research, 60(13), 3384-3388 (2000-07-26)
Overexpression of HER-2/ErbB-2, a homologue of the epidermal growth factor receptor, is associated with poor prognosis, and an ErbB-2-specific antibody is therapeutic when administered to patients with metastatic breast cancer. To understand the mechanism underlying immunotherapy, we concentrated on antibody-
Leonie W Wahjudi et al.
International journal of cancer, 148(6), 1438-1451 (2020-09-20)
DNA sequencing and RNA sequencing are increasingly applied in precision oncology, where molecular tumor boards evaluate the actionability of genetic events in individual tumors to guide targeted treatment. To work toward an additional level of patient characterization, we assessed the
Erin-Mai F Lim et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(9), E1707-E1716 (2017-02-01)
AlphaB-crystallin (αBC) is a small heat shock protein that is constitutively expressed by peripheral nervous system (PNS) axons and Schwann cells. To determine what role this crystallin plays after peripheral nerve damage, we found that loss of αBC impaired remyelination

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