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Merck
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04-078

Sigma-Aldrich

Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal

culture supernatant, Upstate®

Synonym(e):

Anti-AIS, Anti-AR8, Anti-DHTR, Anti-HUMARA, Anti-HYSP1, Anti-KD, Anti-NR3C4, Anti-SBMA, Anti-SMAX1, Anti-TFM

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Upstate®

Methode(n)

western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_000044.2
NM_001011645.1

UniProt-Hinterlegungsnummer

P10275

Versandbedingung

wet ice

Posttranslationale Modifikation Target

phosphorylation (pSer81)

Angaben zum Gen

human ... AR(367)

Spezifität

Androgen Receptor when phosphorylated on Ser81.

Immunogen

A synthetic phospho-peptide surrounding Ser81 of human Androgen Receptor.

Anwendung

Anti-phospho-Androgen Receptor (Ser81) Antibody detects level of phospho-Androgen Receptor (Ser81) & has been published & validated for use in WB.

Qualität

Routinely evaluated by immunoblot.

Zielbeschreibung

99 kDa

Physikalische Form

100μl of cell culture supernatant with 0.1% sodium azide

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Analysenzertifikate (COA)

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Shinichiro Yamamoto et al.
Cancer science, 110(11), 3476-3485 (2019-08-28)
Octamer transcription factor 1 (OCT1) is an androgen receptor (AR)-interacting partner and regulates the expression of target genes in prostate cancer cells. However, the function of OCT1 in castration-resistant prostate cancer (CRPC) is not fully understood. In the present study
Joanne N Davis et al.
Cancer research, 66(24), 11897-11906 (2006-12-21)
Activation of E2F transcription factors, through disruption of the retinoblastoma (Rb) tumor-suppressor gene, is a key event in the development of many human cancers. Previously, we showed that homozygous deletion of Rb in a prostate tissue recombination model exhibits increased
Shen Gao et al.
Journal of molecular endocrinology, 36(3), 463-483 (2006-05-25)
Androgen receptor (AR) is a ligand-activated transcription factor that mediates the action of androgens and is essential for the growth, function, and cell differentiation of the prostate gland. Here, we demonstrated that the prostate apoptosis response factor-4 (par-4) functions as
Theodoros Karantanos et al.
Oncotarget, 7(29), 46321-46334 (2016-06-23)
Caveolin-1 (Cav-1) is overexpressed in aggressive and metastatic prostate cancer (PCa) and induces PCa cell proliferation. Androgens mediate lipid synthesis through acetyl-CoA carboxylase-1 (ACC1) and fatty acid synthase (FASN). We investigated the Cav-1-mediated lipid synthesis in the development of castration
Remi Adelaiye-Ogala et al.
Cancer research, 78(11), 2886-2896 (2018-03-25)
Androgen receptor (AR) plays a crucial role in the development and progression of prostate cancer. AR expression has also been reported in other solid tumors, including renal cell carcinoma (RCC), but its biological role here remains unclear. Through integrative analysis
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