1610001

Scopolamin -hydrobromid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): (−)-Scopolamin -hydrobromid Trihydrat, Hyoscin -hydrobromid, Scopin-tropat
• Empirische Formel (Hill-System): C₁₇H₂₁NO₄ · HBr · 3H₂O
• CAS-Nummer: 6533-68-2
• Molekulargewicht: 438.31
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751078
• MDL number: MFCD00150066
• Beilstein/REAXYS Number: 6100669

Eigenschaften

• grade: pharmaceutical primary standard
• API family: scopolamine, hyoscine
• manufacturer/tradename: USP
• mp: 195-199 °C (dry matter) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1
• InChI key: LACQPOBCQQPVIT-SEYKEWMNSA-N
• Gene Information: human ... CHRM1(1128)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Scopolamine hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Belladonna Extract
• Belladonna Extract Tablets
• Belladonna Leaf
• Belladonna Tincture
• Homatropine Hydrobromide
• Methscopolamine Bromide
• Methscopolamine Bromide Tablets

Biochem/physiol Actions

Kompetitiver, nichtselektiver muskarinischer Acetylcholin-Antagonist. Scopolamin-induzierte Amnesie bei Labortieren ist ein häufig verwendetes Modell von Gedächtnis-Defizit.

Competitive nonselective muscarinic acetylcholine antagonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330
• pcodes: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable