1406005

Methazolamid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): N-(4-Methyl-2-sulfamoyl-Δ²-1,3,4-thiadiazolin-5-yliden)-acetamid
• Empirische Formel (Hill-System): C₅H₈N₄O₃S₂
• CAS-Nummer: 554-57-4
• Molekulargewicht: 236.27
• MDL-Nummer: MFCD00083416
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329750392
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: methazolamide
• Hersteller/Markenname: USP
• mp (Schmelzpunkt): 208 °C (dec.) (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O
• InChI: 1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+
• InChIKey: FLOSMHQXBMRNHR-QPJJXVBHSA-N
• Angaben zum Gen: human ... CA1(759) , CA2(760) , CA4(762) , CA7(766)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Methazolamide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Methazolamide Tablets

Biochem./physiol. Wirkung

Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332,H351
• P-Sätze: P201 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable