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Merck

1338007

USP

Imipramin -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepin-5-propanamin -hydrochlorid, 5-[3-(Dimethylamino)-propyl]-10,11-dihydro-5H-dibenz[b,f]azepin -hydrochlorid

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Empirische Formel (Hill-System):
C19H24N2 · HCl
CAS-Nummer:
113-52-0
Molekulargewicht:
316.87
NACRES:
NA.24
PubChem Substance ID:
329750156
UNSPSC Code:
41116107
MDL number:
MFCD00012669

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InChI key

XZZXIYZZBJDEEP-UHFFFAOYSA-N

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2CCc3ccccc13

InChI

1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

grade

pharmaceutical primary standard

API family

imipramine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... SLC6A2(6530), SLC6A4(6532)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Imipramine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Imipramine Hydrochloride Tablets
  • Imipramine Hydrochloride Injection
  • Desipramine Hydrochloride
  • Clomipramine Hydrochloride
  • Desipramine Hydrochloride Tablets
  • Trimipramine Maleate

Biochem/physiol Actions

Tricyclisches Antidepressivum; hemmt die Serotonin- und Noradrenalin-Transporter mit Kis von 7.7 nM bzw. 67 nM. Hat wenig Einfluss auf Dopamin-Transporter (Ki = 25 μM).
Tricyclisches Antidepressivum; hemmt die Serotonin- und Noradrenalin-Transporter, hat wenig Einfluss auf Dopamin-Transporter.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Lagerklasse

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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