1152033

5-Me Bz Dc Beta-Cyanoethyl Phosphoramidite

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): (5-Methyl-5′-O-Dimethoxytrityl-N4 -benzoyl-2′-deoxycytidine-3′-O-(2-cyanoethyl-N,Ndiisopropyl)phosphoramidite)
• Empirische Formel (Hill-System): C₄₇H₅₄N₅O₈P
• CAS-Nummer: 105931-57-5
• Molekulargewicht: 847.93
• MDL number: MFCD11505862
• UNSPSC Code: 41116107
• NACRES: NA.24

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• form: solid
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical
• format: neat
• storage temp.: −20°C
• SMILES string: P(N(C(C)C)C(C)C)(O[C@@H]1[C@H](O[C@H](C1)[n]5[c](nc(c(c5)C)NC(=O)c6ccccc6)=O)COC(c4ccc(cc4)OC)(c3ccc(cc3)OC)c2ccccc2)OCCC#N
• InChI key: AGMUHEZFYUECLW-QUZMAVINSA-N

Beschreibung

General description

This compound is the 5-methyl analog of benzoyl-protected deoxycytidine phosphoramidite, commonly used to introduce 5-methylcytosine into oligonucleotides during synthesis.

The USP biologics oligonucleotides category includes a variety of synthetic nucleic acid sequences that are essential in research, diagnostics, and therapeutic applications. These oligonucleotides play crucial roles in molecular biology, including gene expression regulation, antisense therapy, and RNA interference. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of oligonucleotide products throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

This product is part of USP Biologics Program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

USP issued SDS can be found here

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable