1012780

Alendronatnatrium

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Alendronat Natriumsalz Trihydrat, 4-Amino-1-hydroxy-1-phosphonobutylphosphonsäure, Mononatriumsalz, MK-217
• Empirische Formel (Hill-System): C₄H₁₂NaNO₇P₂ · 3 H₂O
• CAS-Nummer: 121268-17-5
• Molekulargewicht: 325.12
• NACRES: NA.24
• PubChem Substance ID: 329748953
• UNSPSC Code: 41116107
• MDL number: MFCD01748233

Eigenschaften

• grade: pharmaceutical primary standard
• API family: alendronate
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
• InChI: 1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
• InChI key: DCSBSVSZJRSITC-UHFFFAOYSA-M
• Gene Information: human ... FDPS(2224)

Beschreibung

General description

Alendronate sodium is a primary amino bisphosphonate.[1]

Application

Alendronate sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Natriumalendronat Trihydrat ist ein Knochenresorptionshemmer; Farnesyldiphosphatsynthase Inhibitor (IC₅₀ = 460 nM); CD45 Protein-Tyrosin-Phosphataseinhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable