X4002

Xanthin

≥99%, synthetic (organic), powder

• Synonym(e): 2,6-Dihydroxy-purin
• Empirische Formel (Hill-System): C₅H₄N₄O₂
• CAS-Nummer: 69-89-6
• Molekulargewicht: 152.11
• NACRES: NA.51
• PubChem Substance ID: 24902144
• UNSPSC Code: 41106305
• EC Number: 200-718-6
• MDL number: MFCD00078453
• Beilstein/REAXYS Number: 8733
• Assay: ≥99%
• Biological source: synthetic (organic)
• Form: powder
• Solubility: 1 M NaOH: 0.1 M, clear, colorless to light yellow

Eigenschaften

• Produktname: Xanthin, BioUltra, ≥99%
• biological source: synthetic (organic)
• Quality Segment: 200
• product line: BioUltra
• assay: ≥99%
• form: powder
• impurities: ≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter
• ign. residue: ≤0.1%
• solubility: 1 M NaOH: 0.1 M, clear, colorless to light yellow
• anion traces: sulfate (SO₄^2-): <0.05%
• cation traces: Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%
• SMILES string: O=C1NC(=O)c2nc[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
• InChI key: LRFVTYWOQMYALW-UHFFFAOYSA-N

Beschreibung

General description

Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:

• Guanine deamination by guanine deaminase
• Hypoxanthine conversion by xanthine oxidoreductase

Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.

Application

Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems:

• yeast culture[1]
• human cell line culture
• recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli

Biochem/physiol Actions

Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.

Features and Benefits

• Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
• Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves