T7313

1-[2-(Trifluoromethyl)phenyl]imidazole

• Synonym(e): TRIM
• Empirische Formel (Hill-System): C₁₀H₇F₃N₂
• CAS-Nummer: 25371-96-4
• Molekulargewicht: 212.17
• NACRES: NA.77
• PubChem Substance ID: 24278754
• UNSPSC Code: 12352202
• MDL number: MFCD00041206

Eigenschaften

• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥98% (GC)
• form: solid
• solubility: DMSO: soluble 30 mg/mL
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)c1ccccc1-n2ccnc2
• InChI: 1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H
• InChI key: WZBWBNCQUTXYEL-UHFFFAOYSA-N
• Gene Information: human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

Beschreibung

Biochem/physiol Actions

Potent nitric oxide synthase inhibitor.

Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves