T4949

Taprostene sodium salt

≥98% (HPLC)

• Synonym(e): Rheocyclan, Sodium 3-[(Z)-[(3aR,4R,5R,6aS)-4-[(1E,3S)-3-cyclohexyl-3-hydroxy-1-propenyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-ylidene]methyl]benzoate
• Empirische Formel (Hill-System): C₂₄H₂₉NaO₅
• CAS-Nummer: 87440-45-7
• Molekulargewicht: 420.47
• MDL-Nummer: MFCD05664743
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24724631
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Farbe: off-white
• mp (Schmelzpunkt): 173-182.5 °C (lit.)
• Löslichkeit: H₂O: 26 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: [Na+].[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)C3CCCCC3)[C@@]1([H])C\C(O2)=C\c4cccc(c4)C([O-])=O
• InChI: 1S/C24H30O5.Na/c25-21(16-6-2-1-3-7-16)10-9-19-20-13-18(29-23(20)14-22(19)26)12-15-5-4-8-17(11-15)24(27)28;/h4-5,8-12,16,19-23,25-26H,1-3,6-7,13-14H2,(H,27,28);/q;+1/p-1/b10-9+,18-12-;/t19-,20-,21-,22-,23+;/m1./s1
• InChIKey: KPQVOJYDUCZQEQ-REHYUDDHSA-M

Beschreibung

Anwendung

Taprostene has been used as an IP receptor agonist and was found to increase cAMP expression in human bronchial epithelial cells¹.

Biochem./physiol. Wirkung

Highly selective IP₁ prostanoid receptor agonist.

Angaben zur Herstellung

Taprostene is soluble in water at 26 mg/ml.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves