SML3556

Compound 18

≥98% (HPLC)

• Synonym(e): MPO-IN-28, N-(7-Methoxy-4-methyl-2-quinazolinyl)guanidine
• Empirische Formel (Hill-System): C₁₁H₁₃N₅O
• CAS-Nummer: 37836-90-1
• Molekulargewicht: 231.25
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Quality level: 100

Eigenschaften

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• storage temp.: -10 to -25°C
• SMILES string: N(c1nc2c(c(n1)C)ccc(c2)OC)\C(=N\[H])\N
• InChI: 1S/C11H13N5O/c1-6-8-4-3-7(17-2)5-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16)
• InChI key: ZJBMSSBTCGJZEE-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Agonist of Aedes aegypti mosquitoes NPY-like receptor 7 (NPYLR7) that inhibit mosquito attraction to humans; potent inhibitor of myeloperoxidase (MPO)

Compound 18 is an agonist of Aedes aegypti mosquitoes NPY-like receptor 7 (NPYLR7) that inhibit mosquito attraction to humans and other hosts. Compound 18 suppresses biting and blood-feeding on a live host. Also, It (MPO-IN-28) is a potent myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable