Specific for KIR6.1; does not cross react with KIR6.2.
Immunogen
peptide, (C)KRNSMRRNNSMRRSN, corresponding to amino acid residues 382-396 of rat KIR6.1. This sequence has 15/16 residues identical in human, pig, rabbit, and mouse.
Physikalische Form
Lyophilized from phosphate buffered saline containing 1% bovine serum albumin and 0.025% sodium azide.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Ion channels are a large family of transmembrane proteins, accessible by soluble membrane-impermeable molecules, and thus are targets for development of therapeutic drugs. Ion channels are the second most common target for existing drugs, after G protein-coupled receptors, and are
Frontiers in physiology, 9, 1475-1475 (2018-11-13)
The study explored the anti-hypertrophic effect of the melanocortin MC5R stimulation in H9c2 cardiac myocytes exposed to high glucose. This has been done by using α-MSH and selective MC5R agonists and assessing the expression of GLUT4 and GLUT1 transporters, miR-133
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 23(6), 797-806 (2015-07-30)
Previous studies indicate that ion channels are mediators of bioelectricity promoting wound closure/regeneration in nonmammalian, lower vertebrate systems. The role of ion channels however in regeneration of wounds in mammalian systems that do not regenerate as adults is not yet
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