O2751

Natrium-Oxamat

≥98%

• Synonym(e): Aminooxoessigsäure Natriumsalz, Oxalsäure-monoamid Natriumsalz, Oxamidsäure Natriumsalz
• Lineare Formel: NH₂COCOONa
• CAS-Nummer: 565-73-1
• Molekulargewicht: 111.03
• UNSPSC Code: 12352202
• NACRES: NA.77
• PubChem Substance ID: 24278607
• EC Number: 209-290-5
• Beilstein/REAXYS Number: 6538153
• MDL number: MFCD00044553

Eigenschaften

• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥98%
• form: powder
• mp: 300 °C
• solubility: water: 50 mg/mL, clear, colorless
• SMILES string: [Na+].NC(=O)C([O-])=O
• InChI: 1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1
• InChI key: RQVZIJIQDCGIKI-UHFFFAOYSA-M

Beschreibung

Application

Sodium oxamate has been used:

• as one of the variable in flow injection analysis
• in in vitro angiogenesis assay
• to confirm the stimulatory role of stearic acid on lactate dehydrogenase mediated lactate production

Biochem/physiol Actions

Sodium oxamate influences the fatty acid metabolism. It might be useful for the treatment of diabetes.

Structural analog of pyruvate, inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway[1]. Binding studies with lactate dehydrogenase[2]; Mechanism of inhibition of mitochondrial pyruvate metabolism[3]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)