Fortfahren mit
N4766
N-Nitroso-N-methylurea
Bulk package
Synonym(e):
MNU, N-Methyl-N-nitrosourea
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Über diesen Artikel
Empirische Formel (Hill-System):
C2H5N3O2
CAS-Nummer:
Molekulargewicht:
103.08
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Form:
solid
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenform
solid
contains
aqueous acetic acid as stabilizer
storage temp.
2-8°C
SMILES string
CN(N=O)C(N)=O
InChI
1S/C2H5N3O2/c1-5(4-7)2(3)6/h1H3,(H2,3,6)
InChI key
ZRKWMRDKSOPRRS-UHFFFAOYSA-N
Biochem/physiol Actions
DNA alkylating agent that is carcinogenic in many animal species. Although it can induce benign and malignant tumors in most organs, MNU is most often used to model mammary tumor initiation and progression.
Packaging
Weight on dry basis.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Flam. Sol. 2 - Repr. 1B
Lagerklasse
4.1B - Flammable solid hazardous materials
wgk
WGK 1
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges
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Carcinogenesis, 33(11), 2242-2249 (2012-07-27)
Multiple lines of evidence support a role for curcumin in cancer chemoprevention. Nonetheless, despite its reported efficacy and safety profile, clinical translation of curcumin has been hampered by low oral bioavailability, requiring infeasible 'mega' doses for achieving detectable tissue levels.
Bianca F Gonçalves et al.
The Prostate, 73(11), 1202-1213 (2013-04-27)
Characterization of novel rodent models for prostate cancer studies requires evaluation of either spontaneous and carcinogen-induced tumors as well as tumor incidence in different prostatic lobes. We propose a new short-term rodent model of chemically induced prostate carcinogenesis in which
Marzena Kurowska et al.
Mutation research, 738-739, 52-70 (2012-10-23)
We present studies aimed at determining the types and frequencies of mutations induced in the barley genome after treatment with chemical (N-methyl-N-nitrosourea, MNU) and physical (gamma rays) mutagens. We created M(2) populations of a doubled haploid line and used them