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N4037
Anti-Netrin-G1a antibody produced in goat
affinity isolated antibody, lyophilized powder
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Über diesen Artikel
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
3
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
indirect ELISA: 0.5-1 μg/mL using recombinant mouse netrin-G1a, western blot: 0.1-0.2 μg/mL using recombinant mouse netrin-G1a
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Ntng1(80883)
General description
Netrin-G1a (NTNG1) is also known as laminet 1. It is expressed in axons and is a trans-synaptic adhesion protein. NTNG1 is part of the glycosylphosphatidylinositol-anchored subfamily of the UNC-6/netrin family.
Immunogen
purified, insect cell line Sf 21-derived, recombinant mouse Netrin-G1a.
Biochem/physiol Actions
Netrin-G1a (NTNG1) stimulates the outgrowth of axons in the thalamo-cortical region of the brain and helps to excite the post-synaptic regions.
This antibody shows less than 2% cross-reactivity with rmNetrin-1, rhNetrin-2, and rhNetrin-4.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Verwandter Inhalt
Instructions
Kunio Yaguchi et al.
Molecular brain, 7, 19-19 (2014-03-20)
Higher brain function is supported by the precise temporal and spatial regulation of thousands of genes. The mechanisms that underlie transcriptional regulation in the brain, however, remain unclear. The Ntng1 and Ntng2 genes, encoding axonal membrane adhesion proteins netrin-G1 and
Hiroshi Matsukawa et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(47), 15779-15792 (2014-11-21)
Synaptic cell adhesion molecules are increasingly gaining attention for conferring specific properties to individual synapses. Netrin-G1 and netrin-G2 are trans-synaptic adhesion molecules that distribute on distinct axons, and their presence restricts the expression of their cognate receptors, NGL1 and NGL2
Elena Seiradake et al.
The EMBO journal, 30(21), 4479-4488 (2011-09-29)
Brain wiring depends on cells making highly localized and selective connections through surface protein-protein interactions, including those between NetrinGs and NetrinG ligands (NGLs). The NetrinGs are members of the structurally uncharacterized netrin family. We present a comprehensive crystallographic analysis comprising
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N4037-100UG | 04061833385159 |