N176

Naloxonazine dihydrochloride hydrate

powder, ≥95% (HPLC)

• Synonym(e): bis[(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazone hydrate dihydrochloride
• Empirische Formel (Hill-System): C₃₈H₄₂N₄O₆ · 2HCl · xH₂O
• CAS-Nummer: 880759-65-9
• Molekulargewicht: 723.69 (anhydrous basis)
• UNSPSC Code: 12352202
• PubChem Substance ID: 24278602
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• assay: ≥95% (HPLC)
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• storage condition: desiccated
• color: off-white to light tan
• solubility: H₂O: >2 mg/mL
• storage temp.: −20°C
• SMILES string: O.Cl.Cl.CC(=C)CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CC\C4=N/N=C6\CC[C@@]7(O)[C@H]8Cc9ccc(O)c%10O[C@@H]6[C@]7(CCN8CC=C)c9%10)c35
• InChI: 1S/C39H44N4O6.2ClH.H2O/c1-4-15-42-16-13-36-30-22-5-7-26(44)32(30)48-34(36)24(9-11-38(36,46)28(42)18-22)40-41-25-10-12-39(47)29-19-23-6-8-27(45)33-31(23)37(39,35(25)49-33)14-17-43(29)20-21(2)3;;;/h4-8,28-29,34-35,44-47H,1-2,9-20H2,3H3;2*1H;1H2/b40-24+,41-25+;;;/t28-,29-,34+,35+,36+,37+,38-,39-;;;/m1.../s1
• InChI key: FZEFFWGHDWIOOD-VCOBIVQDSA-N
• Gene Information: human ... OPRM1(4988)

Beschreibung

Biochem/physiol Actions

Potent opioid antagonist that is selective for μ₁ opioid receptors.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)