Fortfahren mit
M4758
(±)-6-Methyl-5,6,7,8-Tetrahydropterin -dihydrochlorid
~95% (TLC)
Synonym(e):
6-MPH4, DL-2-Amino-4-hydroxy-6-methyl-5,6,7,8-tetrahydropteridine dihydrochloride
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 50 mg | Warenkorb auf Verfügbarkeit prüfen | € 255,00 | |
| 100 mg | Warenkorb auf Verfügbarkeit prüfen | € 340,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C7H11N5O · 2HCl
CAS-Nummer:
Molekulargewicht:
254.12
UNSPSC Code:
12352204
NACRES:
NA.51
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5648114
Assay:
~95% (TLC)
€ 255,00
Warenkorb auf Verfügbarkeit prüfen
Technischer Dienst
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Unterstützung erhaltenassay
~95% (TLC)
Quality Level
storage temp.
−20°C
SMILES string
Cl.Cl.CC1CNc2nc(N)nc(O)c2N1
InChI
1S/C7H11N5O.2ClH/c1-3-2-9-5-4(10-3)6(13)12-7(8)11-5;;/h3,10H,2H2,1H3,(H4,8,9,11,12,13);2*1H
InChI key
MKQLORLCFAZASZ-UHFFFAOYSA-N
Application
6-MPH4 is used to study mechanisms of nitric oxide (NO) synthase and free radical induced L-DOPA release from striatal tissue.
Biochem/physiol Actions
Synthetic cofactor for tyrosine hydrolase; also cofactor for phenylalanine and tryptophan hydroxylases; less activity than the natural cofactor, BH4
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Dieser Artikel | |||
|---|---|---|---|
| assay ~95% (TLC) | assay ≥95% | assay 98% | assay 96% |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. - | storage temp. - |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M Bauer et al.
Journal of neurochemistry, 82(5), 1300-1310 (2002-10-03)
Glial cell line-derived neurotrophic factor (GDNF) protects dopaminergic neurones against toxic and physical damage. In addition, GDNF promotes differentiation and structural integrity of dopaminergic neurones. Here we show that GDNF can support the function of primary dopaminergic neurones by triggering
Elizabeth A Gaskell et al.
PloS one, 4(3), e4801-e4801 (2009-03-12)
The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes encoding tyrosine hydroxylase; that produces L-DOPA. The encoded enzymes metabolize phenylalanine as well as tyrosine with substrate preference for tyrosine. Thus the enzymes catabolize phenylalanine to
M Naoi et al.
Journal of chromatography, 427(2), 229-238 (1988-06-03)
A simple assay procedure for tyrosine hydroxylase activity in crude tissue samples was devised that requires minimal sample preparation and use of high-performance liquid chromatography with coulometric electrochemical detection. After incubation of enzyme samples, such as human brain homogenates or
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M4758-50MG | 04061833272879 |
| M4758-100MG | 04061833272862 |