M1568

Mannose-Triflat

For PET imaging, ≥98% (TLC)

• Synonym(e): 1,3,4,6-Tetra-O-acetyl-2-O-trifluormethansulfonyl-β-D-mannopyranose, β-D-Mannopyranose 1,3,4,6-tetra-O-acetat 2-O-Trifluormethansulfonat, Mannosetriflat, TATM
• Empirische Formel (Hill-System): C₁₅H₁₉F₃O₁₂S
• CAS-Nummer: 92051-23-5
• Molekulargewicht: 480.36
• UNSPSC Code: 41116107
• NACRES: NA.12
• PubChem Substance ID: 24896669
• MDL number: MFCD00012353
• Beilstein/REAXYS Number: 4341413
• Assay: ≥98% (TLC)
• Form: powder

Eigenschaften

• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• technique(s): PET imaging: suitable
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@@H](OS(=O)(=O)C(F)(F)F)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
• InChI: 1S/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/m1/s1
• InChI key: OIBDVHSTOUGZTJ-PEBLQZBPSA-N

Beschreibung

General description

Mannose triflate is a glucose analogue.

Application

Mannose triflate is a well-known precursor for ¹⁸F-FDG synthesis for PET applications. The binding of ¹⁸F to the mannose triflate has been carried out via SN₂ nucleophilic substitution reaction. It is used in computational tomography, an imaging technique in early detection of cancer.

Other Notes

This formulation of mannose triflate has reduced trace impurities that are known to cause lower synthetic yields.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)