L3042

Levostin

≥99% (HPLC), solid

• Synonym(e): Levocabastin -hydrochlorid, Levophta, R50547, [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorphenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidincarbonsäure
• Empirische Formel (Hill-System): C₂₆H₂₉N₂O₂F·HCl
• CAS-Nummer: 79547-78-7
• Molekulargewicht: 456.98
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817402
• MDL number: MFCD07787408
• Assay: ≥99% (HPLC)
• Form: solid

Eigenschaften

• assay: ≥99% (HPLC)
• form: solid
• color: white
• solubility: DMSO: soluble ~10 mg/mL
• originator: Johnson & Johnson
• SMILES string: Cl[H].C[C@@H]1CN(CC[C@]1(C(O)=O)c2ccccc2)[C@@H]3CC[C@@](CC3)(C#N)c4ccc(F)cc4
• InChI: 1S/C26H29FN2O2.ClH/c1-19-17-29(16-15-26(19,24(30)31)21-5-3-2-4-6-21)23-11-13-25(18-28,14-12-23)20-7-9-22(27)10-8-20;/h2-10,19,23H,11-17H2,1H3,(H,30,31);1H/t19-,23-,25-,26-;/m1./s1
• InChI key: OICFWWJHIMKBCD-VALQNVSPSA-N
• Gene Information: human ... HRH1(3269)

Beschreibung

Biochem/physiol Actions

Non-peptide histamine H₁ receptor antagonist; neurotensin NTS₂ receptor ligand.

Features and Benefits

This compound is featured on the Neurotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves