L2407

Luzindole

≥90%, melatonin receptor antagonist

• Synonym(e): N-Acetyl-2-benzyltryptamine, N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide
• Empirische Formel (Hill-System): C₁₉H₂₀N₂O
• CAS-Nummer: 117946-91-5
• Molekulargewicht: 292.37
• UNSPSC Code: 12352200
• PubChem Substance ID: 24896315
• NACRES: NA.77
• MDL number: MFCD00672498
• Assay: ≥90%

Eigenschaften

• Produktname: Luzindole, ≥90%
• Quality Segment: 200
• assay: ≥90%
• solubility: DMSO: 5 mg/mL
• storage temp.: −20°C
• SMILES string: CC(=O)NCCc1c(Cc2ccccc2)[nH]c3ccccc13
• InChI: 1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
• InChI key: WVVXBPKOIZGVNS-UHFFFAOYSA-N
• Gene Information: human ... MTNR1A(4543), MTNR1B(4544)

Beschreibung

Application

Luzindole has been used as a MT1/MT2 receptor antagonist to detect the role of the melatonin receptor in neutrophil migration

Biochem/physiol Actions

Luzindole is a melatonin (mel) receptor antagonist. It has higher affinity towards the Mel 1b receptor than the Mel 1a receptor subtype.

Features and Benefits

This compound is featured on the Melatonin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)