IAK0108

Phagocytosis Assay Kit

Green Zymosan, sufficient for 100 fluorometric assays

• NACRES: NA.84
• UNSPSC Code: 12352207

Eigenschaften

• suitability: suitable for fluorescence
• storage temp.: 2-8°C

Beschreibung

General description

Phagocytosis is a cellular process for ingesting and eliminating microorganisms, foreign substances, and apoptotic cells. It is a specific form of endocytosis initiated by recognition and binding of foreign particles by cell surface receptors, followed by their engulfment, and formation of phagosomes. Maturing phagosomes transform to phagolysosomes which destroy the pathogen through enzymes and toxic peroxides. Zymosan prepared from yeast cell wall (Saccharomyces cerevisiae) and consisting of protein-carbohydrate complexes is frequently used as a pathogen in phagocytosis assays.

Application

The Phagocytosis Assay Kit (Green Zymosan) uses fluorescently pre-labeled Zymosan particles to detect and quantify in vitro phagocytosis by fluorescent microscope, spectrophotometer (Ex/Em = 490/520 nm) or flow cytometry.

This kit is suitable for screening activators and/or inhibitors of phagocytosis and Toll-like receptor ligands (TLR) in mammalian cells.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Danger
• hcodes: H350
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 1B
• Lagerklasse: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects