I6909

Monoclonal Anti-Interleukin-2 antibody produced in mouse

clone 5355, purified immunoglobulin, lyophilized powder

• Synonym(e): Anti-IL2, Anti-Lymphokine, Anti-TCGF
• NACRES: NA.41
• UNSPSC Code: 51111800
• Conjugate: unconjugated
• Clone: 5355, monoclonal
• Application: ELISA (c), IHC
• Citations: 3

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 5355, monoclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): capture ELISA: 2-8 μg/mL, immunohistochemistry: 8-25 μg/mL
• isotype: IgG2a
• UniProt accession no.: P60568
• storage temp.: −20°C
• Gene Information: human ... IL2(3558)

Beschreibung

Immunogen

purified, E. coli-derived recombinant human interleukin-2.

Biochem/physiol Actions

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4⁺ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signaling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signaling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)