I0661

(−)-Indolactam V

≥96% (HPLC)

• Synonym(e): (2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
• Empirische Formel (Hill-System): C₁₇H₂₃N₃O₂
• CAS-Nummer: 90365-57-4
• Molekulargewicht: 301.38
• NACRES: NA.77
• PubChem Substance ID: 329815323
• UNSPSC Code: 12352200
• MDL number: MFCD00151197
• Assay: ≥96% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥96% (HPLC)
• form: powder
• color: white
• storage temp.: −20°C
• SMILES string: CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23
• InChI: 1S/C17H23N3O2/c1-10(2)16-17(22)19-12(9-21)7-11-8-18-13-5-4-6-14(15(11)13)20(16)3/h4-6,8,10,12,16,18,21H,7,9H2,1-3H3,(H,19,22)/t12-,16-/m0/s1
• InChI key: LUZOFMGZMUZSSK-LRDDRELGSA-N

Beschreibung

Biochem/physiol Actions

(−)-Indolactam V is naturally present in Streptoverticillium blastmyceticum. It serves as a precursor to the teleocidin class which are alkaloids.[1] It is a the pharmacophore of lyngbyatoxin and teleocidins.[1]

(-)-Indolactam V is a PKC activator shown to effect differentiation in embryonic stem cells leading to development of pancreatic precursors.

(-)-Indolactam V is a PKC activator shown to effect differentiation in embryonic stem cells leading to development of pancreatic precursors. It is active in the mouse model.

Features and Benefits

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable