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H9006

7-(β-Hydroxyethyl)-theophyllin

solid

Synonym(e):

1,3-Dimethyl-7-(2-hydroxyethyl)-xanthin

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Über diesen Artikel

Empirische Formel (Hill-System):
C9H12N4O3
CAS-Nummer:
Molekulargewicht:
224.22
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
208-269-8
MDL number:
Form:
solid


form

solid

color

white

solubility

H2O: soluble (Solutions may be stored for several days at 4°C.), ethanol: moderately soluble (Solutions may be stored for several days at 4°C.)

SMILES string

CN1C(=O)N(C)c2ncn(CCO)c2C1=O

InChI

1S/C9H12N4O3/c1-11-7-6(8(15)12(2)9(11)16)13(3-4-14)5-10-7/h5,14H,3-4H2,1-2H3

InChI key

NWPRCRWQMGIBOT-UHFFFAOYSA-N

Gene Information

human ... ADORA2B(136)

Application

Useful synthetic intermediate in the preparation of 7-substituted xanthines.

Biochem/physiol Actions

Pharmacological profile similar to theophylline.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Binding of theophylline, ethophylline and diprophylline to human serum albumin.
M V Alvarez et al.
Il Farmaco; edizione pratica, 43(7-8), 259-265 (1988-07-01)
E Hashimoto et al.
Biochemical and biophysical research communications, 204(1), 318-324 (1994-10-14)
Adenosine induced by hypoxia exerts various effects via different types of receptors. Recently, hypoxia was shown to be a strong inducer of vascular endothelial growth factor, a secreted endothelial cell specific mitogen. In this report, we studied on effects of
A Apicella et al.
Biomaterials, 14(2), 83-90 (1993-01-01)
An interpretation of the drug release from monolithic water-swellable and soluble polymer tablets is presented. A convenient parameter, alpha, which compares the drug-diffusive conductance in the gel layer with the swelling and dissolving characteristics of the unpenetrated polymer was used



Global Trade Item Number

SKUGTIN
H9006-25G04061833811672

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