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G9003

D-Glutamin

≥98% (HPLC)

Synonym(e):

D-Glutaminsäure-5-amid

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Über diesen Artikel

Empirische Formel (Hill-System):
C5H10N2O3
CAS-Nummer:
Molekulargewicht:
146.14
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
1723796
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Produktname

D-Glutamin, ≥98% (HPLC)

Quality Level

assay

≥98% (HPLC)

form

powder

color

white

application(s)

cell analysis

SMILES string

N[C@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1

InChI key

ZDXPYRJPNDTMRX-GSVOUGTGSA-N

General description

Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids.[1]

Application

D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.[2]

Biochem/physiol Actions

Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%.[1]

Other Notes

unnatürliches Glutamin-Isomer

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Dieser Artikel
M2004605166G1149
form

powder

form

powder

form

solid

form

powder

assay

≥98% (HPLC)

assay

99.0-100.5% (titration)

assay

95% (CP)

assay

≥99% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

color

white

color

-

color

-

color

white

application(s)

cell analysis

application(s)

-

application(s)

-

application(s)

-


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Chinese Hamster Ovary (CHO) cells are the preferred cell line for production of biopharmaceuticals. These cells are capable to grow without serum supplementation, but drastic changes in their phenotype occur during adaptation to protein-free growth, which typically include the change



Global Trade Item Number

SKUGTIN
G9003-5G04061832722504
G9003-1G04061833650035
G9003-10G04061832722498

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