Fortfahren mit
F0267
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys
≥97% (HPLC)
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Über diesen Artikel
Empirische Formel (Hill-System):
C43H65N7O9
CAS-Nummer:
Molekulargewicht:
824.02
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥97% (HPLC)
storage temp.
−20°C
SMILES string
CCCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCC)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(CCCCN)C(O)=O
Biochem/physiol Actions
Potent chemoattractant for human neutrophils.
Radioiodinated molecule has full biological activity.
Radioiodinated molecule has full biological activity.
Lagerklasse
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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V Radhika et al.
American journal of hematology, 52(3), 155-164 (1996-07-01)
Binding of chemoattractant to polymorphonuclear leukocytes (PMNL) triggers a series of events like polymerization of actin and tubulin, orientation of cells, chemotaxis, increase in fluid pinocytosis and phagocytosis, and stimulation of microbicidal pathways which includes lysosomal degranulation and generation of
L A Sklar et al.
Proceedings of the National Academy of Sciences of the United States of America, 78(12), 7540-7544 (1981-12-01)
Antifluorescein antibody molecules were used to interrupt the stimulation of neutrophils by a fluoresceinated chemotactic peptide. From the results we construct a semiquantitative relationship among ligand-receptor interaction, the time course of cell triggering and response, and aspects of cellular adaptation.
A Volz
Journal of cell science, 106 ( Pt 2), 493-501 (1993-10-01)
The study analyses the distribution and quantitative expression of surface CD18 of neutrophils exposed to distinct stimuli that produce different types of continuous shape changes, including types that are associated with locomotion and others that are not. The chemotactic peptide