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EHU075271

MISSION® esiRNA

targeting human TNIP1

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PackungsgrößeSKUVerfügbarkeitPreis
20 μg
Versand in der Regel in 3 Wochen (4 bis 6 Wochen bei kundenspez. Bestellungen).
€ 212,00
50 μg
Versand in der Regel in 3 Wochen (4 bis 6 Wochen bei kundenspez. Bestellungen).
€ 382,00

Über diesen Artikel

NACRES:
NA.51
UNSPSC Code:
41105324

€ 212,00

Versand in der Regel in 3 Wochen (4 bis 6 Wochen bei kundenspez. Bestellungen).
​
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Unterstützung erhalten

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAGTGAGCTGCTGGAAGTGAACAAGCAGTGGGACCAGCATTTCCGGTCCATGAAGCAGCAGTATGAGCAGAAGATCACTGAGCTGCGTCAGAAGCTGGCTGATTTGCAGAAGCAGGTGACTGACCTGGAGGCCGAGCGGGAGCAGAAGCAGCGTGACTTTGACCGCAAGCTCCTCCTGGCCAAGTCCAAGATTGAAATGGAGGAGGCAAGTACCGACAAGGAGCAGCTGACAGCAGAGGCCAAGGAGCTGCGCCAAAAGGTCAAGTACCTGCAGGATCAGCTGAGCCCACTCACCCGACAGCGTGAGTACCAGGAAAAGGAGATCCAGCGGCTCAACAAGGCCCTGGAGGAAGCACTGAGCATCCAAACCCCGCCATCATCTCCACCAACAGCATTTGGGAGCCCAGAAGGAGCAGGGGCCCTCCTAAGGAAACAGGAGCTGGTCA

Ensembl | human accession no.

ENSG00000145901

NCBI accession no.

NM_006058

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... TNIP1(10318)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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esiRNA cDNA target sequence

CAGTGAGCTGCTGGAAGTGAACAAGCAGTGGGACCAGCATTTCCGGTCCATGAAGCAGCAGTATGAGCAGAAGATCACTGAGCTGCGTCAGAAGCTGGCTGATTTGCAGAAGCAGGTGACTGACCTGGAGGCCGAGCGGGAGCAGAAGCAGCGTGACTTTGACCGCAAGCTCCTCCTGGCCAAGTCCAAGATTGAAATGGAGGAGGCAAGTACCGACAAGGAGCAGCTGACAGCAGAGGCCAAGGAGCTGCGCCAAAAGGTCAAGTACCTGCAGGATCAGCTGAGCCCACTCACCCGACAGCGTGAGTACCAGGAAAAGGAGATCCAGCGGCTCAACAAGGCCCTGGAGGAAGCACTGAGCATCCAAACCCCGCCATCATCTCCACCAACAGCATTTGGGAGCCCAGAAGGAGCAGGGGCCCTCCTAAGGAAACAGGAGCTGGTCA

esiRNA cDNA target sequence

TCAAGTGAGCCAAGGGAAGTTACATAGTTTGGTCAAGCCCAGTGTAGACTACGTCTGCCAGCTGAAATTCCCTTCTGGCAATTACCCTCCATGTATAGGTGATAATCGAGATCTGCTTGTCCATTGGTGCCATGGCGCCCCTGGGGTAATCTACATGCTCATCCAGGCCTATAAGGTATTCAGAGAGGAAAAGTATCTCTGTGATGCCTATCAGTGTGCTGATGTGATCTGGCAATATGGGTTGCTGAAGAAGGGATATGGGCTGTGCCACGGTTCTGCAGGGAATGCCTATGCCTTCCTGACACTCTACAACCTCACACAGGACATGAAGTACCTGTATAGGGCCTGTAAGTTTGCTGAATGGTGCTTAGAGTATGGAGAACATGGATGCAGAACACCAGACACCCCTT

esiRNA cDNA target sequence

CATTCTGGTGGACCTGGAACCCGGAACCATGGACAGTGTCCGCTCAGGGGCCTTTGGACATCTCTTCAGGCCTGACAATTTCATCTTTGGTCAGAGTGGGGCCGGCAACAACTGGGCCAAGGGTCACTACACGGAGGGGGCGGAGCTGGTGGATTCGGTCCTGGATGTGGTGCGGAAGGAGTGTGAAAACTGCGACTGCCTGCAGGGCTTCCAGCTGACCCACTCGCTGGGGGGCGGCACGGGCTCCGGCATGGGCACGTTGCTCATCAGCAAGGTGCGTGAGGAGTATCCCGACCGCATCATGAACACCTTCAGCGTCGTGCCCTCACCCAAGGTGTCAGACACGGTGGTGGAGCCCTACAACGCCACGCTGTCCATCCACCAGCTGGTGGAGAACACGGATGAGACCTACTGCATCGACAACGAG

esiRNA cDNA target sequence

CCCGTGCTCTATAGCCTCATGTCCAGCCGCTTCCGAGAGACCTTCCAGGAGGCCCTGTGCCTCGGGGCCTGCTGCCATCGCCTCAGACCCCGCCACAGCTCCCACAGCCTCAGCAGGATGACCACAGGCAGCACCCTGTGTGATGTGGGCTCCCTGGGCAGCTGGGTCCACCCCCTGGCTGGGAACGATGGCCCAGAGGCGCAGCAAGAGACCGATCCATCCTGAGTGGAGCCTTAAAGTGGCTTCACCTGGAGGGGCCAGAGGGTCACCTGGAGCTGGGGAGACACATCTGCCTTCCTCTGCAGGGATGCCTTCACGTACTGTCCCTAGTTCAGCCTAGAAATTCTGACCAGCACCTCAGTTTCCCTCAGAGGGAAACAGCAGGAGGAGGGATCCCTGACTGCTGAGGACTCACACTGACCAGACGCCACACCTTGTGCTTCTTATCTGTCCACTGCCACTCCCCCAGTTCAAATCCTTACCCTGCAGAAATATCACAGTTAGCTGGGGCTCAGCAGTCCTCCCTCTGGGGACTCCCTGCCACCACTGCCAGTTTCTGAA

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Ensembl | human accession no.

ENSG00000145901

Ensembl | human accession no.

ENSG00000115365

Ensembl | human accession no.

ENSG00000198211, ENSG00000258947

Ensembl | human accession no.

ENSG00000171596

Gene Information

human ... TNIP1(10318)

Gene Information

human ... LANCL1(10314)

Gene Information

human ... TUBB3(10381)

Gene Information

human ... NMUR1(10316)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

NCBI accession no.

NM_006058

NCBI accession no.

NM_006055

NCBI accession no.

NM_001197181, NM_006086

NCBI accession no.

NM_006056

Lagerklasse

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Die Dokumentenbibliothek aufrufen

Ellen M Westerhout et al.
Nucleic acids research, 33(2), 796-804 (2005-02-03)
HIV-1 replication can be efficiently inhibited by intracellular expression of an siRNA targeting the viral RNA. However, HIV-1 escape variants emerged after prolonged culturing. These RNAi-resistant viruses contain nucleotide substitutions or deletions in or near the targeted sequence. We observed
Rambon Shamilov et al.
Mediators of inflammation, 2020, 5919150-5919150 (2020-05-08)
TNIP1 protein is a widely expressed, cytoplasmic inhibitor of inflammatory signaling initiated by membrane receptors such as TLRs which recognize pathogen-associated and damage-associated molecular patterns (PAMPs and DAMPs). Keratinocyte TNIP1 deficiency sensitizes cells to PAMPs and DAMPs promoting hyperresponsive expression
Lilla Erdei et al.
Frontiers in immunology, 9, 2155-2155 (2018-10-16)
Human skin cells recognize the presence of the skin microbiome through pathogen recognition receptors. Epidermal keratinocytes are known to activate toll-like receptors (TLRs) 2 and 4 in response to the commensal Cutibacterium acnes (C. acnes, formerly known as Propionibacterium acnes)

Global Trade Item Number

SKUGTIN
EHU075271-50UG04061828392070
EHU075271-20UG04061828679034

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