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E5641
11,12-Epoxy-(5Z,8Z,14Z)-eicosatrienoic acid
~100 μg/mL in ethanol, ≥95%
Synonym(e):
(±)11,12-EpETrE, 11,12-EET
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Über diesen Artikel
Empirische Formel (Hill-System):
C20H32O3
CAS-Nummer:
Molekulargewicht:
320.47
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
200-578-6
MDL number:
Quality Level
assay
≥95%
concentration
~100 μg/mL in ethanol
lipid type
omega FAs
storage temp.
−20°C
SMILES string
CCCCC\C=C\CC1OC1C\C=C\C\C=C\CCCC(O)=O
InChI
1S/C20H32O3/c1-2-3-4-5-9-12-15-18-19(23-18)16-13-10-7-6-8-11-14-17-20(21)22/h6,8-10,12-13,18-19H,2-5,7,11,14-17H2,1H3,(H,21,22)/b8-6+,12-9+,13-10+
InChI key
DXOYQVHGIODESM-ATELOPIESA-N
Packaging
Packaged under argon
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Lagerklasse
3 - Flammable liquids
wgk
WGK 1
flash_point_f
48.2 °F - closed cup
flash_point_c
9 °C - closed cup
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Verwandter Inhalt
Yindi Ding et al.
The Journal of pharmacology and experimental therapeutics, 350(1), 14-21 (2014-04-26)
Cytochrome P450-derived epoxides of arachidonic acid [i.e., the epoxyeicosatrienoic acids (EETs)] are important lipid signaling molecules involved in the regulation of vascular tone and angiogenesis. Because many actions of 11,12-cis-epoxyeicosatrienoic acid (EET) are dependent on the activation of protein kinase
Yong Zhou et al.
Shock (Augusta, Ga.), 47(5), 638-645 (2016-10-19)
Acute lung injury (ALI) is characterized by rapid alveolar injury, vascular leakage, lung inflammation, neutrophil accumulation, and induced cytokines production leading to lung edema. The mortality rate of patients suffering from ALI remains high. Epoxyeicosatrienoic acids (EETs) are cytochrome P450-dependent
L Yang et al.
British journal of clinical pharmacology, 80(1), 28-44 (2015-02-07)
There is increasing evidence suggesting that epoxyeicosatrienoic acids (EETs) play an important role in cardioprotective mechanisms. These include regulating vascular tone, modulating inflammatory responses, improving cardiomyocyte function and reducing ischaemic damage, resulting in attenuation of animal models of cardiovascular risk
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E5641-25UG | 04061838070814 |