E4375

(−)-Epinephrin -(+)-bitartratsalz

solid, adrenergic receptor agonist

• Synonym(e): L-3,4-Dihydroxy-α-(methylaminomethyl)benzylalkohol-Wasserstoff D -bitartrat (Salz), L-Adrenalin -(+)-bitartratsalz, L-Adrenalin D-bitartrat, L-Epinephrin D-bitartrat
• Empirische Formel (Hill-System): C₉H₁₃NO₃ · C₄H₆O₆
• CAS-Nummer: 51-42-3
• Molekulargewicht: 333.29
• NACRES: NA.77
• PubChem Substance ID: 24277774
• UNSPSC Code: 12352200
• EC Number: 200-097-1
• MDL number: MFCD00035077
• Form: solid

Eigenschaften

• Produktname: (−)-Epinephrin -(+)-bitartratsalz, solid
• form: solid
• Quality Segment: 200
• color: white
• solubility: H₂O: soluble, alcohol: soluble
• storage temp.: 2-8°C
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
• InChI key: YLXIPWWIOISBDD-NDAAPVSOSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)

Beschreibung

General description

Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.

Application

(-)Epinephrine (+)-bitartrate salt has been used:

• to test the possible existence of β-adrenergic vasodilation
• to infuse into the adipose region to minimize blood loss and tissue contamination
• as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates
• in the measurement of total superoxide dismutase (tSOD) enzymatic activity

Biochem/physiol Actions

Adrenergischer Rezeptoragonist.

Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

Light sensitive

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 1 Oral
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges