D6000

2′-Deoxyadenosine 5′-di­phos­phate sodium salt

• Synonym(e): dADP
• Empirische Formel (Hill-System): C₁₀H₁₅N₅O₉P₂ · xNa⁺
• CAS-Nummer: 72003-83-9
• Molekulargewicht: 411.20 (free acid basis)
• EG-Nummer: 276-280-5
• MDL-Nummer: MFCD00083610
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24893990
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥95% (HPLC)
• Form: powder
• Lagertemp.: −20°C
• SMILES String: [Na].Nc1ncnc2n(cnc12)C3CC(O)C(COP(O)(=O)OP(O)(O)=O)O3
• InChI: 1S/C10H15N5O9P2.Na.H/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(23-7)2-22-26(20,21)24-25(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H2,11,12,13)(H2,17,18,19);;
• InChIKey: KZGAPWRJMWSNQO-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2′-Deoxyadenosine5′-di­phos­phate (dADP) is a purine containing adenine as the nucleobase. It isproduced as a product of hypoxanthine oxidase action on hypoxanthine duringpurine degradation in the body.

Anwendung

2′-Deoxyadenosine 5′-diphosphate (dADP) may be used for the synthesis of deoxyadenylate oligonucleotides with enzymes such as polynucleotide phosphorylase from Escherichia coli. dADP is used as an inhibitor of bacterial poly(A) polymerase. DeoxyADP may be use as an alternative substrate or inhibitor for studies of ATPase and DNA and RNA polymerase specificity.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331,H315,H319,H335
• P-Sätze: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges