D1542

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride

≥98% (TLC), Glycogen phosphorylase inhibitor, solid

• Synonym(e): 2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride
• Empirische Formel (Hill-System): C₅H₁₁NO₃ · HCl
• CAS-Nummer: 100991-92-2
• Molekulargewicht: 169.61
• UNSPSC Code: 12352202
• PubChem Substance ID: 24278359
• NACRES: NA.77
• MDL number: MFCD03427380

Eigenschaften

• Produktname: 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride, enzyme inhibitor
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: solid
• storage condition: under inert gas
• solubility: water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: Cl.OC[C@H]1NC[C@@H](O)[C@@H]1O
• InChI: 1S/C5H11NO3.ClH/c7-2-3-5(9)4(8)1-6-3;/h3-9H,1-2H2;1H/t3-,4-,5-;/m1./s1
• InChI key: PZGVJCJRMKIVLJ-DEVUXVJFSA-N
• Gene Information: human ... PYGB(5834), PYGBL(5835), PYGL(5836), PYGM(5837) ; mouse ... Gaa(14387), Glb1(12091), Treh(58866) ; rat ... Man2a1(25478), Pygl(64035), Si(25588)

Beschreibung

General description

1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.

Application

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.

Biochem/physiol Actions

Inhibitor of glycogen phosphorylase and α-glucosidases.

Disclaimer

Extremely hygroscopic, store and handle under argon

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)