D0444
DT-2 -trifluoracetat (Salz)
≥95% (HPLC), film
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Über diesen Artikel
Empirische Formel (Hill-System):
C122H223N53O23 · xC2HF3O2
Molekulargewicht:
2800.42 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
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Unterstützung erhaltenassay
≥95% (HPLC)
form
film
composition
Peptide content, ≥60%
color
colorless to white
solubility
H2O: 0.5 mg/mL, clear
shipped in
wet ice
storage temp.
−20°C
Quality Level
Verwandte Kategorien
1 of 4
Dieser Artikel | |||
|---|---|---|---|
| form film | form film | form film | form film |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: 0.5 mg/mL, clear | solubility - | solubility - | solubility - |
| color colorless to white | color colorless | color yellow | color yellow |
Biochem/physiol Actions
Cell permeable cGMP protein kinase (PKG) inhibitor
Features and Benefits
This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Mark S Taylor et al.
Molecular pharmacology, 65(5), 1111-1119 (2004-04-23)
Cyclic GMP-dependent protein kinase (PKG) serves as an important physiological regulator of vascular reactivity and tone. However, available inhibitors of PKG have exhibited variable effects in intact tissue, hindering the elucidation of the functional role of PKG in blood vessels.
W R Dostmann et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(26), 14772-14777 (2000-12-20)
Arrays of octameric peptide libraries on cellulose paper were screened by using (32)P-autophosphorylated cGMP-dependent protein kinase Ialpha (cGPK) to identify peptide sequences with high binding affinity for cGPK. Iterative deconvolution of every amino acid position in the peptides identified the
Christin Christensen et al.
Stem cells and development, 15(5), 647-654 (2006-11-16)
Previously, we have shown that increasing the intracellular cGMP concentration enhances the sonic hedgehog (Shh) response in neural plate cells. The use of two mouse embryonic stem (ES) cell lines allowed a highly sensitive and reproducible quantification of the Shh
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