C7673

Monoclonal Anti-CD14 antibody produced in mouse

clone UCHM-1, purified immunoglobulin, buffered aqueous solution

• Synonym(e): Monoclonal Anti-CD14
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: UCHM-1, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 55 kDa
• Speziesreaktivität: human
• Methode(n): flow cytometry: 5 μL using 1 × 10⁶ cells
• Isotyp: IgG2a
• UniProt-Hinterlegungsnummer: P08571
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CD14(929)

Beschreibung

Spezifität

The epitope recognized by this clone is sensitive to routine formalin fixation and paraffin embedding. Cryostat sections, post-fixed in formalin can be stained.
3rd Workshop: code no. 203
4th Workshop: code no. M24

Immunogen

human thymocytes followed by peripheral blood T cells.

Anwendung

Monoclonal Anti-CD14 antibody produced in mouse is suitable for the following applications:

• Flow cytometry at a dilution of 5μL using 1 × 106 cells
• Immunofluorescence.
• Immunoblotting.

Biochem./physiol. Wirkung

CD14 gene has an important role during signaling of the innate immune response and in the detection of inflammatory pathogens. It also plays an important role in recognizing tuberculosis (TB) disease and it can be used as a potential biomarker for predicting the prognosis of breast invasive ductal carcinoma with LN+ER/PR-Her²⁺. It is also associated with asthma, croup and allergy.

Zielbeschreibung

CD14 is a phosphoinositol-linked, single-chain, human cell surface glycoprotein antigen which is found on most human peripheral blood monocytes, granulocytes and dendritic reticulum cells, and some tissue macrophages. CD14 may also be present on B cells. Soluble forms of CD14 are present in serum and urine. The antigen functions as an acceptor for LPS-binding protein complexes.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable