C1355

Z-Leu-Glu(O-Me)-His-Asp(O-Me) fluoromethyl ketone trifluoroacetate salt hydrate

≥90%

• Synonym(e): Z-LEHD-FMK, Z-LE(OMe)HD(OMe)-FMK
• Empirische Formel (Hill-System): C₃₂H₄₃FN₆O₁₀ · xC₂HF₃O₂ · yH₂O
• CAS-Nummer: 210345-04-3
• Molekulargewicht: 690.72 (anhydrous free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329774878
• MDL number: MFCD01862609

Eigenschaften

• assay: ≥90%
• form: film
• storage condition: desiccated
• color: colorless to light brown
• solubility: DMSO: 10 mg/mL, clear
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COC(=O)CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
• InChI: 1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)/t22-,23-,24-,25-/m0/s1
• InChI key: YXRKBEPGVHOXSV-QORCZRPOSA-N

Beschreibung

Application

A cell-permeable inhibitor of caspase-9, which exhibits competitive and irreversible inhibition.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)